Platelet-rich plasma therapy has moved from niche sports medicine into mainstream care in Scottsdale, with clinics now offering it for everything from knee osteoarthritis and tendon injuries to facial rejuvenation and hair restoration. With that growth comes a wide quality range, since the same procedure name can mean very different things depending on the provider's training, the equipment used, and whether injections are performed under ultrasound or fluoroscopic guidance.
For this 2026 editorial review, we evaluated 10 Scottsdale clinics based on provider credentials, PRP specialization, technology, transparency, and verified patient feedback across Google, Yelp, and Birdeye. Pricing is rarely listed publicly in this category, so most figures below require a consultation to confirm.
Table of Contents
| Company | Best For | Pricing | Rating |
| Integrated Spine, Pain & Wellness (ISPW) | Holistic pain management with PRP | Available on request | 3.7 stars on Yelp (3 reviews) |
| Desert Spine & Sports Physicians | Orthopedic and sports PRP | Pricing options noted as available on their website blog ... | 4.6 stars on Yelp (180 reviews) |
| DHH Med Spa | Aesthetic PRP and PRF injectables | Reviewed during in-clinic consultation | 4.7 stars on Yelp (117 reviews) |
| The Shaw Center | Closed-system PRP technology | Available on request | 4.6 stars on Yelp (28 reviews) |
| Precision Regenerative Medicine | Knee and musculoskeletal PRP | Available on request | 3.0 stars on Yelp (2 reviews) |
| Phoenix Skin (PHX Skin) | PRP for hair restoration and scar revision | Available on request | 4.1 stars on Yelp (53 reviews) |
| Clear Dermatology & Aesthetics Center | PRP within a full-service dermatology practice | Available on request | 4.8 stars on Google |
| ReGen Pain & Wellness | Integrative chiropractic and regenerative care | Not publicly listed; CareCredit financing reportedly available... | 5.0 stars on Yelp (9 reviews) |
| Skin Charm | Boutique aesthetic PRP with a membership model | Membership tiers at $50/month and $200/month; per-service... | 4.3 stars on Yelp (25 reviews) |
| R3 Stem Cell | Broad regenerative medicine menu (with caveats) | Available on request | 4.8 stars on Birdeye (64 reviews) |
| Location: | 7425 E Shea Blvd, Suite 102, Scottsdale, AZ 85260 |
| Service Area: | Scottsdale |
| Phone: | (480) 660-8823 |
| Rating: | 3.7 stars on Yelp (3 reviews) |
| Pricing: | Available on request |
| Website: | ispwscottsdale.com |
Integrated Spine, Pain & Wellness is a pain management practice led by Dr. Ashu Goyle, a board-certified anesthesiologist affiliated with the Cleveland Clinic, with advanced spine training. The clinic markets a Functional Spinal Unit Approach alongside PRP, bone marrow therapy, MLS M6 laser therapy, and lifestyle and diet counseling.
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| Location: | 8670 E Shea Blvd, Suite 102, Scottsdale, AZ 85260 (Phoenix office: 3700 N 24th St, Suite 210) |
| Service Area: | Greater Phoenix and Scottsdale |
| Phone: | (602) 726-4075 |
| Rating: | 4.6 stars on Yelp (180 reviews) |
| Pricing: | Pricing options noted as available on their website blog |
| Website: | desertspineandsports.com |
Desert Spine & Sports Physicians has been offering PRP injections for more than a decade, with a clinical focus on spine care and sports medicine. Their work centers on PRP for soft tissue and tendon injuries, supported by ultrasound-guided and fluoroscopically-guided techniques, plus related procedures like Bone Marrow Aspirate Concentrate (BMAC) and prolotherapy. This is one of the more orthopedically-focused PRP options in the Scottsdale area.
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| Location: | 9188 E San Salvador Dr, Suite 102, Scottsdale, AZ 85258 |
| Service Area: | Scottsdale |
| Phone: | (480) 336-4195 |
| Rating: | 4.7 stars on Yelp (117 reviews) |
| Pricing: | Reviewed during in-clinic consultation |
| Website: | dhhmedspa.com |
Originally founded as Desert Holistic Health around 2015, DHH Med Spa has roughly 11 years in business and an aesthetic focus that includes both PRP and PRF injections. The practice is led by Megan Davies, FNP-BC, a Certified Aesthetic Nurse Specialist, and has been recognized by AZ Foothills Magazine and featured on local ABC news coverage.
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| Location: | 8913 E Bell Road, Suite 201, Scottsdale, AZ 85260 |
| Service Area: | Scottsdale |
| Phone: | (480) 767-1900 |
| Rating: | 4.6 stars on Yelp (28 reviews) |
| Pricing: | Available on request |
| Website: | theshawcenter.com |
The Shaw Center is a plastic surgery practice led by a board-certified plastic surgeon and is one of the few clinics in Scottsdale marketing the Magellan TruPRP closed-system device for platelet concentration. They offer both PRP and PRF, including the PRP shot for women's intimate health, alongside a full surgical and non-surgical aesthetic menu.
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| Location: | 8591 E Bell Rd, Suite 104, Scottsdale, AZ 85260 |
| Service Area: | Scottsdale |
| Phone: | (602) 806-7389 |
| Rating: | 3.0 stars on Yelp (2 reviews) |
| Pricing: | Available on request |
| Website: | precisionmedprp.com |
Precision Regenerative Medicine is a small, specialist practice led by Dr. Tammy Penhollow, DO, a US Navy and Stanford-trained board-certified pain and spine physician. The clinic is heavily focused on orthobiologics and musculoskeletal care, and markets a proprietary 'Knee Boost System' for patients with knee pain.
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| Location: | 7312 E Deer Valley Rd, Bldg D, Suite 105, Scottsdale, AZ 85255 |
| Service Area: | North Scottsdale |
| Phone: | (480) 473-9111 |
| Rating: | 4.1 stars on Yelp (53 reviews) |
| Pricing: | Available on request |
| Website: | phxskin.com |
Phoenix Skin is led by Dr. Lee Laris, D.O., a dermatologist with reportedly more than 25 years of clinical experience. The practice has built a reputation around plasma-centric treatments, with PRP applied to hair growth, facial rejuvenation, scar revision, and combination procedures like fat transfer with PRP and microneedling with PRP.
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| Location: | 8841 E Bell Road, Scottsdale, AZ 85260 (additional Paradise Valley location) |
| Service Area: | Scottsdale and Paradise Valley |
| Phone: | (480) 398-1550 |
| Rating: | 4.8 stars on Google (3155 reviews) |
| Pricing: | Available on request |
| Website: | cleardermatology.net |
Clear Dermatology & Aesthetics Center operates as a combined medical and cosmetic dermatology practice, with PRP offered alongside acne and eczema care, skin cancer treatment, microneedling, DiamondGlow, and injectables. The clinic emphasizes evidence-based care and notes that staff personally trial products and services before offering them to patients.
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| Location: | 6560 N Scottsdale Rd STE 125, Scottsdale, AZ 85253 |
| Service Area: | Central and North Scottsdale |
| Phone: | (602) 485-9390 |
| Rating: | 5.0 stars on Yelp (9 reviews); 5.0 stars on Google (54 reviews) |
| Pricing: | Not publicly listed; CareCredit financing available. |
| Website: | regenpainandwellness.com |
ReGen Pain & Wellness combines chiropractic care, nutrition, and regenerative therapies in one practice. The clinic is led by Keith Smigiel, FNP-C, DC, FIAMA, and pairs Neural Prolotherapy and PRP with other modalities such as Therapeutic Plasma Exchange, IV therapy, ozone, and hair restoration.
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| Location: | 7038 E Indian School Rd, Scottsdale, AZ 85251 |
| Service Area: | Old Town Scottsdale |
| Phone: | (480) 687-8996 |
| Rating: | 4.3 stars on Yelp (25 reviews) |
| Pricing: | Membership tiers at $50/month and $200/month; per-service pricing on request |
| Website: | skincharm.com |
Skin Charm is a small, design-forward aesthetic clinic in Old Town Scottsdale that bundles PRP and PRF with a broad menu of injectables, lasers, and wellness offerings. The practice uses a 'Society' membership model intended to encourage ongoing maintenance, and reviewers commonly note a conservative approach to filler and Botox dosing.
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| Location: | 10045 East Dynamite Blvd, Suite 230, Scottsdale, AZ 85262 |
| Service Area: | Scottsdale and a multi-state network |
| Phone: | +1 (844) GET-STEM |
| Rating: | 4.8 stars on Birdeye (64 reviews) |
| Pricing: | Available on request |
| Website: | r3stemcell.com |
R3 Stem Cell offers PRP for soft tissue and joint injuries as part of a wider regenerative medicine menu that also includes stem cell therapy for conditions like arthritis, back pain, and neuropathy. The clinic has been BBB Accredited since 2017 and references Institutional Review Board (IRB) approval for the investigation of regenerative therapies. Prospective patients should be aware of the regulatory history described below.
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Pricing in Scottsdale is rarely posted publicly and varies based on the indication (orthopedic versus aesthetic), the number of injection sites, whether image guidance is used, and how many sessions are recommended. As a general benchmark, ask each provider for a written estimate, a treatment plan with the number of expected sessions, and whether follow-up sessions are included or billed separately.
PRP (platelet-rich plasma) is processed using anticoagulants and centrifugation to concentrate platelets in a liquid suspension. PRF (platelet-rich fibrin) uses a slightly different processing protocol with no anticoagulants, producing a fibrin matrix that releases growth factors more gradually.
Both. PRP is used for orthopedic indications like knee osteoarthritis, tendon injuries, and chronic back pain, as well as aesthetic indications like facial rejuvenation, microneedling enhancement, scar revision, and hair restoration. In Scottsdale specifically, clinics like Desert Spine & Sports Physicians and Precision Regenerative Medicine focus on the orthopedic side, while DHH Med Spa, Phoenix Skin, and Skin Charm lean toward aesthetics. Several practices offer both.
Look for clear physician or nurse practitioner credentials published on the clinic's website, board certification in a relevant specialty (pain medicine, anesthesiology, dermatology, plastic surgery, or sports medicine for orthopedic PRP), and explicit experience with PRP for your specific indication. For joint or tendon injections, ask whether the clinic uses ultrasound or fluoroscopic guidance. Verify any state licensure independently through the Arizona Medical Board or the Arizona Board of Nursing.
Most providers recommend a series rather than a single treatment, with the typical range falling between one and three sessions spaced several weeks apart for orthopedic indications, and three to six sessions for hair restoration or aesthetic protocols. Maintenance treatments are common. Because protocols vary by clinic and indication, ask each provider for their specific recommended schedule and the supporting rationale before committing to a plan.
For orthopedic PRP, Desert Spine & Sports Physicians and Precision Regenerative Medicine offer the strongest credentials and image-guided technique, while ReGen Pain & Wellness suits patients who want an integrative chiropractic and regenerative model. On the aesthetic side, DHH Med Spa, Phoenix Skin, and
The Shaw Center has a distinct edge: a long-running aesthetic injector practice, a dermatologist with deep plasma-treatment experience, and a closed-system PRP device. Whichever clinic you shortlist, request a written treatment plan, ask about provider credentials and injection guidance, and verify pricing in writing before booking.
